Computational & wet-lab immunologist · T cell & NK cell biology · Immuno-oncology · Single-cell multi-omics
Postdoctoral Researcher · University Hospital Bonn, Germany

Immunologist with 6+ years of postdoctoral experience across tumour immunology, viral immunity, and translational immuno-oncology. I pair wet-lab expertise in human primary tissue and genetic engineering with independent, end-to-end single-cell and spatial multi-omics analysis — from raw sequencing on HPC through to publication figures. My focus is the biology of cytotoxic lymphocytes and advancing NK/T cell therapy strategies from discovery to the clinic.

🔬 Open to industry roles in immuno-oncology and cell therapy across the EU and Australia.

970 citations · h-index 15 · 6+ years postdoc · PI on €110k competitive funding

• Cytotoxic lymphocyte biology — NK cell plasticity & dysfunction in the tumour microenvironment, CD8 T cell states, unconventional T cells
• Single-cell & spatial multi-omics — end-to-end scRNA-seq, CITE-seq, scATAC-seq, scTCR-seq and spatial transcriptomics pipelines, run on HPC
• Cell engineering & therapy — CRISPR KO/KI/OE in primary human NK & CD8 T cells, CAR-NK / CAR-T, preclinical models
• Translational immunology — reverse-translational discovery, biomarkers, and clinical immune phenotyping from patient tissue

Computational projects

• nkg7-binder-design — de novo mini-binder design pipeline (RFdiffusion, ProteinMPNN, Boltz-2, Chai-1) run as a SLURM DAG
• nkg7-structural-analysis — in-silico structural and evolutionary characterisation of NKG7, with unit tests and CI
• Thymic_NK_development — do NK cells carry a thymic TCR footprint? Reanalysis of public single-cell data

Analysis code for papers (published papers are archived with Zenodo DOIs)

• Corvino et al., Eur J Immunol 2024 · Turiello, Ng et al., Eur J Immunol 2025 · Braun et al., Immunity 2020 · Giordano, Layer, Leonardelli et al., Nat Commun 2024 · Hosni, Kilian et al., Cancer Res 2023 · Kosiol et al. (under revision)

Reanalyses of public single-cell datasets (shared Seurat workflow, accessions and DOIs tabulated per study)

• NK cell and ILC1 studies — Crinier 2018/2020, Bai, McFarland, Krämer, Dean
• Tumour immune-cell atlases — Tang, Borcherding, Nieto, Abdelfattah, Cillo, Sade-Feldman
• Reference atlases — Hao PBMC CITE-seq, Tabula Muris, Tabula Sapiens

Tools and infrastructure

• r-utility-functions — documented, tested R package of single-cell, bulk RNA-seq and TCGA helpers (docs)
• HPC_workflows — SLURM job templates, conda environments and a tested Python job-script helper
• lab-protocols — standardised wet-lab and computational protocols (site)

More at dilloncorvino.com.

“Understanding cytotoxic lymphocyte biology, from bench to publication.”